Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT)

Incomplete protocol content can impair understanding and implementation of the trial; reduce efficiency of protocol review; and lead to burdensome protocol amendments.

The protocol of a clinical trial is essential for study conduct, review, reporting, and interpretation. SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) is an international initiative that aims to improve the quality of clinical trial protocols by defining an ... Read more


This month, we are amassing resources and expertise about careers in clinical research, whether that's a career as a research coordinator, data manager, lab technician, community health worker, research nurse, investigator, health systems researcher, social scientist - or anything else. ... Read more

Discussion Framework for Clinical Trial Data Sharing: Guiding Principles, Elements, and Activities

Data sharing is one of the most important current issues in clinical trials. If conducted in the right way, sharing data could help facilitate faster and better generation of evidence to bring new interventions and improve disease management.

Have your say about this key issue by reading this blog.